Research Spotlight: Comparing Proton Beam Therapy and Plaque Brachytherapy in Ocular Melanoma

Source: Massachusetts General Hospital , October 2022

What was the question you set out to answer with this study?

Proton beam radiation therapy and plaque brachytherapy using radioactive iodine seeds are both established treatments for ocular melanoma (a rare form of cancer that affects the eye), and both options are available to the patients within our joint MGH-MEE Ocular Melanoma Program.

Our group was interested in characterizing how the dose distribution delivered with these two therapeutic radiation modalities varies depending on the size of the tumor and its location with respect to the critical structures of the eye, such as the optic disc, retina, eye lens.

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