Presence of Many Nevi Increases Risk for Second Primary Melanoma Diagnosis

Source: Oncology Nurse Advisor, December 2022

Risk for developing a subsequent primary melanoma was associated with presence of many nevi, according to results of a population-based prospective cohort study, published in JAMA Dermatology.

The risk for a second primary melanoma is assumed to be associated with history of a first primary melanoma; however, to date, no formal analysis of whether certain patients are at increased risk has been published.

To evaluate predictors for second primary melanoma, investigators from QIMR Berghofer Medical Research Institute in Australia sourced data from the QSkin Sun and Health Study, which randomly sampled adults aged 40 to 69 years between 2010 and 2011 from the electoral roll in Queensland (N=38,845). Diagnoses of primary melanoma were evaluated through 2018.

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