Photosensitizing Drugs, Estrogen, and Diuretics Linked to Increased Skin Cancer Risk

Source: Dermatology Times, March 2025

Estrogen therapy and certain diuretics may increase skin cancer risk, highlighting the need for careful patient counseling and sun exposure management.

A recent prospective study explored the association between commonly prescribed photosensitizing drugs and the risk of developing skin cancer in women.

Published in Photodermatology, Photoimmunology & Photomedicine, the study found that estrogen therapy and certain diuretics significantly increased the risk of basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and cutaneous malignant melanoma (cM).

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