Personalized Immunotherapy Regimens Drive Frontline Melanoma Care
Source: Onc Live, December 2022
Successful melanoma treatment decisions and sequencing are increasingly being guided by individual patient needs and comorbidities, although first-line immunotherapy, be it a combination or single agent, presents clear anticancer benefits, according to Claire F. Verschraegen, MD.
“It’s [important to] discuss the adverse effects [AEs] and make sure patients understand what [their lives will look like] if they [develop an AE from immunotherapy] to gauge how comfortable they will be choosing a single or double agent,” Verschraegen said.
In an interview with OncLive®, Verschraegen discussed how nivolumab (Opdivo) and ipilimumab (Yervoy) fit into the treatment paradigm both in combination and as single agents, posed examples of when treatment-related AEs (TRAEs) might influence which agents to use, and emphasized the importance of considering the benefits of immunotherapy, which often outweigh the associated risks.