New cell-based therapy for melanoma more effective than existing treatment, trial finds

Source: NBC News, September 2022

European researchers announced Saturday that a new treatment for advanced melanoma was more effective than the leading existing therapy in a Phase 3 clinical trial.

The treatment, which uses a patient’s own immune cells to fight the cancer, has some similarities to another type of treatment that has proven to be highly effective for blood cancers, called CAR-T therapy.

CAR-T therapy involves harvesting a patient’s T cells and modifying them in the lab to turn them into cancer fighters, then infusing the cells back into the patient. The personalized treatment was first shown to be successful a decade ago in certain leukemia patients; it’s now also used for lymphomas as well as multiple myeloma.

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