Neuronal-Like Communication Between Non-Neuron Skin Cells May Initiate Melanoma
Source: Dermatology Times, August 2023
According to study authors, this electrical communication between skin cells may have the potential for therapeutic implications.
In melanoma, melanocytes skin cells release melanin-containing vesicles to keratinocytes, neighboring skin cells, to give skin its color. Melanoma commonly has mutations in genes such as BRAF or NRAS.
Previous work had found that the developmental state of the cell plays a dominant role in this process because some melanocytes have a particular landscape that makes them acceptable for tumor development.