Navigating Newer Treatment Regimens in Melanoma: Practical Approaches to Dosing and Adverse Event Management

Source: Cancer Network , June 2025

Adoption of Newer Immunotherapy Regimens

Key Discussion Points:

  • Community adoption of newer immunotherapy combinations
  • Evidence-based decision-making in regimen selection
  • Factors influencing uptake of nivolumab/relatlimab in clinical practice

Key Points for Physicians:

  • Long-term efficacy data from CheckMate 067 continues to influence treatment selection, though growing confidence in nivolumab/relatlimab is emerging with longer follow-up
    Practical advantages of nivolumab/relatlimab include its 30-minute infusion every 4 weeks schedule and improved toxicity profile.

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