Mouse Model May Shed Light on APC mutations in brain metastases

Source: Dermatology Times, June 2022

A grant from the Melanoma Research Foundation powers the initial stages of the project.

A mouse model under development one day may unlock the role of adenomatous polyposis coli (APC) mutations in melanoma brain metastases. A $100,000 pilot award from the Melanoma Research Alliance (MRA), Washington, DC, will allow University of Minnesota researchers to lay groundwork for additional future funding.1

“What this means is, we can afford to do the initial development of the tools, model, and resources so that we can apply for multimillion dollar federal research funds. Without this award, we wouldn’t be able to do that,” said lead investigator James Robinson, PhD. He is assistant professor at The Hormel Institute, University of Minnesota in Austin, Minnesota.