Moffitt Study Shows Immune Structures in Melanoma Could Help Predict Patient Survival

Source: Moffitt Cancer Center, November 2024

TAMPA, Fla. — A new study has found that certain immune structures may be linked to better survival in patients with melanoma, the deadliest form of skin cancer. The study, led by researchers at Moffitt Cancer Center in collaboration with investigators at UPMC Hillman Cancer Center, was published in the Journal for ImmunoTherapy of Cancer.

This is the first time researchers have studied these structures in both early and later-stage melanoma, giving new details about how they might affect patient health.

The study looked at 278 samples from melanoma patients. These samples included early stage tumors on the skin and tumors that had spread to other parts of the body. Researchers focused on two key structures: lymphoid aggregates and tertiary lymphoid structures.

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