Categorized | Scientific Publications

Melanoma Journal Articles for October 2016

The Journal of Biological Chemistry

Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKC? Signaling Axis*

  1. Brian A. Shapiro,1
  2. Ngoc T. Vu1
  3. Michael D. Shultz
  4. Jacqueline C. Shultz,
  5. Jennifer A. Mietla
  6. Mazen M. Gouda
  7. Adly Yacoub
  8. Paul Dent,?,**,
  9. Paul B. Fisher?,**,‡‡2
  10. Margaret A. Park,**3and 
  11. Charles E. Chalfant

First Published onAugust 12, 2016doi: 10.1074/jbc.M116.737569October 7, 2016The Journal of Biological Chemistry291, 21669-21681.


Brand, A. et al. LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells. Cell Metab. (2016)


The prognostic significance of heparanase expression in metastatic melanoma

Olga Vornicova1,*, Ilanit Boyango2*, Sari Feld2, Inna Naroditsky3, Olga Kazarin1, Yaniv Zohar3, Yariv Tiram2, Neta Ilan2, Ofer Ben-Izhak3, Israel Vlodavsky2, Gil Bar-Sela

DOI: 10.18632/oncotarget.12492

Received: September 20, 2016 Accepted: September 26, 2016 Published: October 06, 2016

New England Journal of Medicine

Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy

Alexander M.M. Eggermont, M.D., Ph.D., Vanna Chiarion-Sileni, M.D., Jean-Jacques Grob, M.D., Ph.D., Reinhard Dummer, M.D., Jedd D. Wolchok, M.D., Ph.D., Henrik Schmidt, M.D., Omid Hamid, M.D., Caroline Robert, M.D., Ph.D., Paolo A. Ascierto, M.D., Jon M. Richards, M.D., Céleste Lebbé, M.D., Ph.D., Virginia Ferraresi, M.D., Michael Smylie, M.D., Jeffrey S. Weber, M.D., Ph.D., Michele Maio, M.D., Ph.D., Lars Bastholt, M.D., Laurent Mortier, M.D., Ph.D., Luc Thomas, M.D., Ph.D., Saad Tahir, M.D., Axel Hauschild, M.D., Ph.D., Jessica C. Hassel, M.D., F. Stephen Hodi, M.D., Corina Taitt, M.D., Veerle de Pril, M.Sc., Gaetan de Schaetzen, Ph.D., Stefan Suciu, Ph.D., and Alessandro Testori, M.D.

October 8, 2016DOI: 10.1056/NEJMoa1611299

“Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species”

Irina V Lebedeva, Zao-Zhong Su, Devanand Sarkar, Shinichi Kitada, Paul Dent, Samuel Waxman, John C Reed, Paul B Fisher, Cancer Res., 63 (2003)

Journal of Biological Chemistry

Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth*

Alexander J. LakhterJames Hamilton§Raymond L. KongerNickolay Brustovetsky§Hal E. Broxmeyer and Samisubbu R. Naidu

First Published onAugust 18, 2016doi: 10.1074/jbc.M115.712166October 14, 2016The

Journal of Biological Chemistry291, 21869-21879.

Journal for  ImmunoTherapy of Cancer

Acute visual loss after ipilimumab treatment for metastatic melanoma

Melissa A. Wilson, Kelly Guld, Steven Galetta, Ryan D. Walsh, Julia Kharlip, Madhura Tamhankar, Suzanne McGettigan, Lynn M. Schuchter and Leslie A. Fecher

Journal for ImmunoTherapy of Cancer20164:66

DOI: 10.1186/s40425-016-0170-9

©  The Author(s). 2016

Received: 24 March 2016 Accepted: 29 September 2016

Published: 18 October 2016

Eggermont AMM et al. Prolonged survival in stage III melanoma with ipilimumab adjuvant therapy. N Engl J Med 2016 Oct 8; [e-pub]. (


Trends in incidence, survival, and management of uveal melanoma: a population-based study of 7,516 patients from the Surveillance, Epidemiology, and End Results database (1973–2012)

Authors Mahendraraj K, Lau CSM, Lee I, Chamberlain RS

Received 26 May 2016

Accepted for publication 28 June 2016

Published 25 October 2016 Volume 2016:10 Pages 2113—2119


Int. J. Mol. Sci. 201617(11), 1124; doi:10.3390/ijms17111124

Upregulated MicroRNA-25 Mediates the Migration of Melanoma Cells by Targeting DKK3 through the WNT/?-Catenin Pathway

Jia Huo, Yanfei Zhang, Ruilian Li, Yuan Wang, Jiawen Wu and Dingwei Zhang  

Received: 14 April 2016 / Revised: 20 May 2016 / Accepted: 31 May 2016 / Published: 27 October 2016

Cancer Cell

UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis

Laurence Wurth, Panagiotis Papasaikas, David Olmeda, Nadine Bley, Guadalupe T. Calvo, Santiago Guerrero, Daniela Cerezo-Wallis,Javier Martinez-Useros, María García-Fernández, Stefan üttelmaier, Maria S. Soengas, Fátima Gebauer

Publication stage: In Press Corrected Proof


Malignant Melanoma Arising at the Site of a Previously Excised Giant Congenital Melanocytic Nevus

Carrie C. Coughlin, MD1M. Laurin Council, MD1Alejandro A. Gru, MD2; et alRyan C. Fields, MD3;Susan J. Bayliss, MD1

JAMA Dermatol. 2014;150(1):100-101. doi:10.1001/jamadermatol.2013.5775

Systemic Therapy for Previously Untreated Advanced BRAF-Mutated MelanomaA Systematic Review and Network Meta-Analysis of Randomized Clinical Trials

Tahira Devji, BSc1Oren Levine, MD1,2Binod Neupane, PhD1; et alJoseph Beyene, PhD1;Feng Xie, PhD1,3

JAMA Oncol. Published online October 27, 2016. doi:10.1001/jamaoncol.2016.4877

Journal of Clinical Oncology

Sunscreen Use in the Prevention of Melanoma: Common Sense Rules

Tamar Nijsten

DOI: 10.1200/JCO.2016.69.5874 Journal of Clinical Oncology – published online before print October 31, 2016