Melanoma Journal Articles for September 2020

New England Journal of Medicine

Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma

Reinhard Dummer, M.D., Axel Hauschild, M.D., Mario Santinami, M.D., Victoria Atkinson, M.D., Mario Mandalà, M.D., John M. Kirkwood, M.D., Vanna Chiarion Sileni, M.D., James Larkin, M.D., Ph.D., Marta Nyakas, M.D., Caroline Dutriaux, M.D., Andrew Haydon, M.B., B.S., Ph.D., Caroline Robert, M.D., Ph.D., et al.

September 2, 2020
DOI: 10.1056/NEJMoa2005493


Cancer Discovery

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Gretchen M. Alicea, Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera, Marie R. Webster, Curtis H. Kugel III, Brett L. Ecker, M. Cecilia Caino, Andrew V. Kossenkov, Hsin-Yao Tang, Dennie T. Frederick, Keith T. Flaherty, Xiaowei Xu, Qin Liu, Dmitry I. Gabrilovich, Meenhard Herlyn, Ian A. Blair, Zachary T. Schug, David W. Speicher and Ashani T. Weeraratna

DOI: 10.1158/2159-8290.CD-20-0329 Published September 2020


JAAD

A retrospective multicenter study of fatal pediatric melanoma

Elena B. Hawryluk, MD, PhD, Danna Moustafa, BS, Diana Bartenstein, MD, Zachary Wolner, MD, Jennifer Huang, MD, Ashfaq A. Marghoob, MD, et.al.

Published: July 01, 2020DOI:https://doi.org/10.1016/j.jaad.2020.06.1010


JAAD

Survival in patients with multiple primary melanomas: Systematic review and meta-analysis

Genevieve Peek, MBBS, Catherine M. Olsen, PhD, Peter Baade, PhD, Danny R. Youlden, PhD, Joanne F. Aitken, PhD, Adele C. Green, MBBS, PhD, Kiarash Khosrotehrani, MD, PhD 

Published:April 01, 2020DOI:https://doi.org/10.1016/j.jaad.2020.03.076


MDPI _ Cancers

Targeted Therapies for Melanoma

by Karel Smetana, Jr. 1,2,*,Lukáš Lacina 1,2,3 andOnd?ej Kodet 1,2,3

 

Cancers 202012(9), 2494; https://doi.org/10.3390/cancers12092494

Received: 31 August 2020 / Accepted: 1 September 2020 / Published: 3 September 2020


Molecular and Clinical Oncology

Primary acral amelanotic melanoma: A rare case report

Jiaojiao Zhang, Huizhi Yang, Jiaxi Lin, Fang Zhang, Jianqiang Shi, Rongyi Chen

 

Published online on: September 3, 2020     https://doi.org/10.3892/mco.2020.2129


Oncology

Management of Melanoma during Pregnancy: A Case Series of 11 Women Treated at NYU Langone Health

Sawyers A.E.a,b · Pavlick A.C.a,b,c · Weber J.S.a,c · Osman I.a,b,c · Stein J.A.a,b

 

https://doi.org/10.1159/000506811


Dermatologic Therapy

Gender differences in cutaneous melanoma: Demographics, prognostic factors, and survival outcomes

Sara Behbahani Spandana Maddukuri Joshua B. Cadwell W. Clark Lambert Robert A. Schwartz

First published: 05 August 2020     https://doi.org/10.1111/dth.14131


European Journal of Radiology

Available online 8 September 2020, 109268

Value of MR-based radiomics in differentiating uveal melanoma from other intraocular masses in adults

YapingSuabXiaolinXubcdPanliZuoeYuweiXiaeXiaoxiaQuabQinghuaChenabJianGuoabWenbinWeibcdJunfangXianab

https://doi.org/10.1016/j.ejrad.2020.109268


Cancer epidemiology, biomarkers & prevention

Disparities in the Occurrence of Late Effects Following Treatment among Adolescent and Young Adult Melanoma Survivors

Alicia A. Gingrich, Candice A.M. Sauder, Melanie Goldfarb, Qian Li, Ted Wun and Theresa H.M. Keegan

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DOI: 10.1158/1055-9965.EPI-20-0427


International Journal of Molecular Sciences

Evaluation of Radioiodinated Fluoronicotinamide/ Fluoropicolinamide-Benzamide Derivatives as Theranostic Agents for Melanoma

 Chao-Cheng Chen 1,† , Yang-Yi Chen 1,† , Yi-Hsuan Lo 1 , Ming-Hsien Lin 2,3, Chih-Hsien Chang 1,4 , Chuan-Lin Chen 1 , Hsin-Ell Wang 1 and Chun-Yi Wu 1,*

Received: 24 August 2020; Accepted: 3 September 2020; Published: 9 September 2020

Int. J. Mol. Sci. 2020, 21, 6597; doi:10.3390/ijms21186597


British Journal of Dermatology

Occupation and cutaneous melanoma: a 45?year historical cohort study of 14·9 million people in five Nordic countries

J.H. Alfonso, J.I. Martinsen, E. Weiderpass, E. Pukkala, K. Kjærheim, L. Tryggvadottir, E Lynge

First published: 06 July 2020

https://doi.org/10.1111/bjd.19379


JAMA Dermatology

July 15, 2020

Association of Anti–Programmed Cell Death 1 Antibody Treatment With Risk of Recurrence of Toxic Effects After Immune-Related Adverse Events of Ipilimumab in Patients With Metastatic Melanoma

Angélique Brunot, MD1Jean-Jacques Grob, MD, PhD2Geraldine Jeudy, MD3; et alFlorent Grange, MD, PhD4Bernard Guillot, MD, PhD5Nora Kramkimel, MD6Laurent Mortier, MD, PhD7Yannick Le Corre, MD8François F. Aubin, MD, PhD9Sandrine Mansard, MD10Céleste Lebbé, MD, PhD11Astrid Blom, MD, PhD12Henri Montaudie, MD13Damien Giacchero, MD14Sorilla Prey, MD15Delphine Legoupil, MD16Alexis Guyot, MD17Mona Amini-adle, MD18Florence Granel-Brocard, MD19Nicolas Meyer, MD20Monica Dinulescu, MD21Julien Edeline, MD, PhD1Boris Campillo-Gimenez, MD1Thierry Lesimple, MD, MSc1

JAMA Dermatol. 2020;156(9):982-986. doi:10.1001/jamadermatol.2020.2149


BMC Bioinformatics

Review of medical image recognition technologies to detect melanomas using neural networks

Mila EfimenkoAlexander Ignatev & Konstantin Koshechkin 

BMC Bioinformatics volume 21, Article number: 270 (2020) 


Cancer Immunology, Immunotherapy

Hyperprogressive disease rarely occurs during checkpoint inhibitor treatment for advanced melanoma

  1. SchuivelingE. H. J. TonkR. J. VerheijdenK. P. M. Suijkerbuijk

Cancer Immunology, Immunotherapy (2020)   Published: 14 September 2020


Clinical Cancer Research

Chloroquine sensitizes GNAQ/11-mutated melanoma to MEK1/2 inhibition

Amanda Truong, Jae Hyuk Yoo, Michael Scherzer, John Michael S Sanchez, Kali J Dale, Conan G Kinsey, Jackson R Richards, Donghan Shin, Phaedra Ghazi, Michael D. Onken, Kendall J Blumer, Shannon J. Odelberg and Martin McMahon

DOI: 10.1158/1078-0432.CCR-20-1675


BioRxiv

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

Charlotte M de WindeSamantha L GeorgeAbbey Arp Agnesska C Benjamin Eva Crosas-Molist Yukti Hari-GuptaAlexander Carver,  Valerio ImperatoreVictor G MartinezVictoria Sanz-Moreno,   Sophie E Acton

doi: https://doi.org/10.1101/2020.07.23.218578


Clinical Cancer Research

Chloroquine sensitizes GNAQ/11-mutated melanoma to MEK1/2 inhibition

Amanda Truong, Jae Hyuk Yoo, Michael Scherzer, John Michael S Sanchez, Kali J Dale, Conan G Kinsey, Jackson R Richards, Donghan Shin, Phaedra Ghazi, Michael D. Onken, Kendall J Blumer, Shannon J. Odelberg and Martin McMahon

DOI: 10.1158/1078-0432.CCR-20-1675 September 15, 2020


BioRix

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

Charlotte M. de WindeSamantha L. GeorgeAbbey B. Arp Agnesska C. Benjamin Eva Crosas-Molist Yukti Hari-GuptaAlexander Carver, Valerio ImperatoreVictor G. MartinezVictoria Sanz-MorenoSophie E. Acton

doi: https://doi.org/10.1101/2020.07.23.218578        Posted September 14, 2020.


MDPI – Life

Treatment of Advanced Melanoma: Past, Present and Future 

Taku Fujimura, Yumi Kambayashi, Kentaro Ohuchi, Yusuke Muto and Setsuya Aiba

Received: 2 September 2020; Accepted: 13 September 2020; Published: 16 September 2020

Life 2020, 10, 208; doi:10.3390/life10090208


Cureus

Primary Vaginal Malignant Melanoma: A Case Report and Review of Literature

Mahati ParavathaneniVinay Edlukudige KeshavaBohdan BaraloRajesh Thirumar

Published: September 18, 2020 (see history)

DOI: 10.7759/cureus.10536


The lancet

Adjuvant nivolumab versus ipilimumab in resected stage IIIB–C and stage IV melanoma (CheckMate 238): 4-year results from a multicentre, double-blind, randomised, controlled, phase 3 trial

Prof Paolo A Ascierto, MD , Michele Del Vecchio, MD, Mario Mandalá, MD, Prof Helen Gogas, MD, Ana M Arance, MD, Prof Stephane Dalle, MD, et al.

Published:September 19, 2020 DOI:https://doi.org/10.1016/S1470-2045(20)30494-0


Theranostics 2020; 10(25):11428-11443. doi:10.7150/thno.47432

Research Paper

BET inhibitor suppresses melanoma progression via the noncanonical NF-?B/SPP1 pathway

Guangtong Deng1,2*, Furong Zeng1,2*, Juan Su1,2, Shuang Zhao1,2, Rui Hu1,2, Wu Zhu1,2, Shuo Hu3, Xiang Chen1,2?, Mingzhu Yin1,2?


Histopathology

Comprehensive clinicopathological and molecular analysis of primary malignant melanoma of the oesophagus

Sho Tsuyama Shinji Kohsaka Takuo Hayashi Yoshiyuki Suehara Takashi Hashimoto Yoshiaki Kajiyama Masahiko Tsurumaru Toshihide Ueno  See all authors 

First published: 11 July 2020 

https://doi.org/10.1111/his.14210


Clinical Cancer Research

Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma

Mark R. Middleton, Cheryl McAlpine, Victoria K. Woodcock, Pippa Corrie, Jeffrey R. Infante, Neil M. Steven, Thomas R Jeffry Evans, Alan Anthoney, Alexander N. Shoushtari, Omid Hamid, Avinash Gupta, Antonella Vardeu, Emma Leach, Revashnee Naidoo, Sarah Stanhope, Sion Lewis, Jacob Hurst, Ita O’Kelly and Mario Sznol

DOI: 10.1158/1078-0432.CCR-20-1247


Cancer Research

BETA-GALACTOSYLCERAMIDASE PROMOTES MELANOMA GROWTH VIA MODULATION OF CERAMIDE METABOLISM

Mirella Belleri, Giuseppe Paganini, Daniela Coltrini, Roberto Ronca, Daniela Zizioli, Michela Corsini, Andrea Barbieri, Elisabetta Grillo, Stefano Calza, Roberto Bresciani, Eugenio Maiorano, Mauro G. Mastropasqua, Tiziana Annese, Arianna Giacomini, Domenico Ribatti, Josefina Casas, Thierry Levade, Gemma Fabrias and Marco Presta

DOI: 10.1158/0008-5472.CAN-19-3382

This OnlineFirst version was published on September 30, 2020

 

 

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