Categorized | Scientific Publications

Melanoma Journal Articles for February 2018

Science Translational Medicine

Eradication of spontaneous malignancy by local immunotherapy

Idit Sagiv-Barfi1Debra K. Czerwinski1Shoshana Levy1Israt S. Alam2Aaron T. Mayer2Sanjiv S. Gambhir2 and Ronald Levy1,*
Science Translational Medicine  31 Jan 2018:
Vol. 10, Issue 426, eaan4488
DOI: 10.1126/scitranslmed.aan4488

Journal of Clinical Oncology

Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator’s Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial

James LarkinDavid MinorSandra D’AngeloBart NeynsMichael SmylieWilson H. Miller Jr, et al.
DOI: 10.1200/JCO.2016.71.8023
Journal of Clinical Oncology 36, no. 4 (February 2018) 383-390.

The FEBS Journal

Exosomes derived from B16F0 melanoma cells alter the transcriptome of cytotoxic T cells that impacts mitochondrial respiration

Cassidy L. Bland, Christina N. Byrne-Hoffman, Audry Fernandez, Stephanie L. Rellick, Wentao Deng, David J. Klinke
Accepted manuscript online: 5 February 2018
DOI: 10.1111/febs.1439

Molecular Pharmaceutics

Solid-in-Oil Peptide Nanocarriers for Transcutaneous Cancer Vaccine Delivery against Melanoma

Rie WakabayashiMasato SakuragiShuto KozakaYoshiro TaharaNoriho Kamiya, and Masahiro Goto
Mol. Pharmaceutics, Just Accepted Manuscript
DOI: 10.1021/acs.molpharmaceut.7b00894
Publication Date (Web): February 5, 2018

American Association for Clinical Chemistry – Letters to the Editor

Optimizing Amplification of the GC-Rich TERT Promoter Region Using 7-Deaza-dGTP for Droplet Digital PCR Quantification of TERT Promoter Mutations

Andrew J. Colebatch, Tom Witkowski, Paul M. Waring, Grant A. McArthur, Stephen Q. Wong, Alexander Dobrovic
Papers in Press. Published January 30, 2018 as doi:10.1373/clinchem.2017.284257
Clinical Chemistry 64:4 000–000 (2018)


Systemic treatments for metastatic cutaneous melanoma

Sandro Pasquali, Andreas V Hadjinicolaou, Vanna Chiarion Sileni, Carlo Riccardo Rossi, Simone Mocellin
First published: 6 February 2018
Editorial Group: Cochrane Skin Group
DOI: 10.1002/14651858.CD011123.pub2

British Journal of Dermatology

Wide skin markings pattern – melanoma descriptor or patient-related factor?

A. Rishpon, M. Marchetti, A. Marghoob

Accepted manuscript online: 6 February 2018
DOI: 10.1111/bjd.16420

RSC Advances

SNHG5 promotes proliferation and induces apoptosis in melanoma by sponging miR-155

Lu Yan,*a  Suihai Wang,b  Yue Li,c  Linda Tognetti,d  Rui Tan,a  Kang Zeng,e  Elisa Pianigiani,d  Xiangbin Mi,a  Hui Li,a  Michele Fimianid  and  Pietro Rubegni*d
received on 17 Nov 2017, accepted on 26 Jan 2018 and first published on 07 Feb 2018
DOI: 10.1039/C7RA12520H

Ocular Oncology and Pathology
Original Paper

The Patient’s Experience of Ocular Melanoma in the US: A Survey of the Ocular Melanoma Foundation

Afshar A.R.a · Deiner M.a · Allen G.b · Damato B.E.a, c
Ocul Oncol Pathol 2018;4:280-290 Oncol Pathol 2018;4:280-290

JAMA Oncology

Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti–Programmed Cell Death 1 Antibodies

Jenny H. Lee, MBBS1,2,3Georgina V. Long, PhD2,4,5Alexander M. Menzies, PhD2,4,5; et al
JAMA Oncol. Published online February 8, 2018. doi:10.1001/jamaoncol.2017.5332

Journal of Medicinal Chemistry

Glutathione S-Transferase ?-Activatable O2-(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma In Vitro and In Vivo

Zhangjian HuangJianbing WuYu ZouHaoliang YuanYinqiu ZhangYue FeiAtul BhardwajJatinder KaurEdward E. Knaus, and Yihua Zhang

  1. Med. Chem., Just Accepted Manuscript

DOI: 10.1021/acs.jmedchem.7b01178
Publication Date (Web): February 8, 2018

Oncology Letters

Macrophages in skin melanoma-the key element in melanomagenesis (Review)

Malgorzata Pieniazek, Rafal Matkowski, Piotr Donizy
Published online on: February 9, 2018

Sensors 201818(2), 556; doi:10.3390/s18020556

Skin Lesion Analysis towards Melanoma Detection Using Deep Learning Network

Yuexiang Li   andLinlin Shen 
Received: 19 December 2017 / Revised: 8 February 2018 / Accepted: 8 February 2018 / Published: 11 February 2018

Asian Oncology Research Journal, 1(1): 1-8, 2018; Article no.AORJ.39053
Case Study

Primary Mucosal Melanoma of Upper Alveolar Ridge and Hard Palate – A Case Report

F. Massilamani1, S. Kailasam1, C. K. Vishnu Priya1*and R. Poorani2
DOI: 10.9734/AORJ/2018/39053
Received 28th November 2017 Accepted 5th February 2018 Published 12th February 2018

Journal of Clinical Oncology

Nivolumab Plus Ipilimumab in Patients With Advanced Melanoma: Updated Survival, Response, and Safety Data in a Phase I Dose-Escalation Study

Margaret K. CallahanHarriet KlugerMichael A. PostowNeil H. SegalAlexander LesokhinMichael B. Atkins,
DOI: 10.1200/JCO.2017.72.2850 Journal of Clinical Oncology 36, no. 4 (February 2018) 391-398.


High density of M2-macrophages in acral lentiginous melanoma compared to superficial spreading melanoma

M Zúñiga-Castillo, NV Pereira, MN Sotto

Accepted manuscript online: 7 February 2018
DOI: 10.1111/his.13478

Cancer Research
Research Article

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma

Thibault Houles, SimonPierre Gravel, Geneviève Lavoie, Sejeong Shin, Mathilde Savall, Antoine Méant, Benoit Grondin, Louis Gaboury, Sang-Oh Yoon, Julie St-Pierre and Philippe P Roux
DOI: 10.1158/0008-5472.CAN-17-2215

J Am Acad Dermatol. 2018 Feb 10. pii: S0190-9622(18)30205-6. doi: 10.1016/j.jaad.2018.02.019. [Epub ahead of print]

Whole-exome sequencing reveals differences between nail apparatus melanoma and acral melanoma.

Lee M1Yoon J1Chung YJ1Lee SY2Choi JY2Shin OR3Park HY4Bahk WJ4Yu DS2Lee YB5.
PMID: 29438763
DOI: 10.1016/j.jaad.2018.02.019

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis

Jennifer L McQuade, Carrie R Daniel, PhD, Prof Kenneth R Hess, PhD, Carmen Mak, PhD, Daniel Y Wang, MD, Rajat R Rai, MD, John J Park, MD, Lauren E Haydu, PhD, Christine Spencer, MPH, Matthew Wongchenko, BS, Stephen Lane, MS, Dung-Yang Lee, PhD, Mathilde Kaper, MA, Meredith McKean, MD, Kathryn E Beckermann, MD, Samuel M Rubinstein, MD, Isabelle Rooney, MD, Luna Musib, PhD, Nageshwar Budha, PhD, Jessie Hsu, PhD, Theodore S Nowicki,
Published: 12 February 2018


Adjuvant Therapy in Resected Melanoma

Ana Rita J. Maria, M.D., Catarina Viegas Dias, M.D., Bruno Heleno, M.D., Ph.D., NOVA Medical School, Lisbon, Portugal
February 15, 2018
N Engl J Med 2018; 378:678-680
DOI: 10.1056/NEJMc1716071


Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy

Xin Hong, Ryan J. Sullivan, Mark Kalinich, Tanya Todorova Kwan, Anita Giobbie-Hurder, Shiwei Pan, Joseph A. LiCausi, John D. Milner, Linda T. Nieman, Ben S. Wittner, Uyen Ho, Tianqi Chen, Ravi Kapur, Donald P. Lawrence, Keith T. Flaherty, Lecia V. Sequist, Sridhar Ramaswamy, David T. Miyamoto, Michael Lawrence, Mehmet Toner, Kurt J. Isselbacher, Shyamala Maheswaran and Daniel A. Haber
PNAS 2018; published ahead of print February 16, 2018,

British Journal of Dermatology

Beyond country-specific incidence and mortality: the global burden of melanoma


K.J.L. Bell, A.E. Cust

First published: 14 February 2018
DOI: 10.1111/bjd.15688


Case Report

Severe Adverse Reaction to Vemurafenib in a Pregnant Woman with Metastatic Melanoma

de Haan J.a,b · van Thienen J.V.c · Casaer M.d · Hannivoort R.A.e · Van Calsteren K.f · van Tuyl M.g ·van Gerwen M.M.h · Debeer A.i · Amant F.b,h,j · Painter R.C.k
Case Rep Oncol 2018;11:119–124

Journal of Neuro-oncology

The impact of timing of immunotherapy with cranial irradiation in melanoma patients with brain metastases: intracranial progression, survival and toxicity

Rifaquat Rahman, Alfonso Cortes, Andrzej Niemierko, Kevin S. Oh, Keith T. Flaherty, Donald P. Lawrence, Ryan J. Sullivan, Helen A. Shih

British Journal of Dermatology

Prognostic features for acral lentiginous melanoma

A.E. Cust

First published: 14 February 2018
DOI: 10.1111/bjd.16163

Virchows Archiv A

Survival with primary cutaneous malignant melanoma, evaluated from 2012 cases

A multivariate regression analysis
Søndergaard, K. & Schou, G. Vichows Archiv A Pathol Anat (1985) 406: 179.
June 1985, Volume 406, Issue 2, pp 179–195

JAMA Dermatology
Brief Report
February 16, 2018

Examining the Incidence and Presentation of Melanoma in the Cardiothoracic Transplant Population

Charles J. Puza, BA1Adela R. Cardones, MD2Paul J. Mosca, MD, PhD, MBA3
JAMA Dermatol. Published online February 16, 2018. doi:10.1001/jamadermatol.2018.0130

Clin Exp Dermatol. 2018 Feb 16. doi: 10.1111/ced.13393. [Epub ahead of print]

Association of clinicopathological features of melanoma with total naevus count and a history of dysplastic naevi: a cross-sectional retrospective study within an academic centre.

Tan SY1Strazzulla LC2Li X3,4Park JJ5Lee SJ1,3Kim CC6.
PMID: 29450912
DOI: 10.1111/ced.13393


Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype

Tobias Sinnberg, Mitchell P. Levesque, Jelena Krochmann, Phil F. Cheng, Kristian Ikenberg, Francisco Meraz-Torres, Heike Niessner, Claus Garbe and Christian Busch
Molecular Cancer201817:59
Received: 2 October 2017
Accepted: 29 January 2018
Published: 17 February 2018

Pigment cell & melanoma research

A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in patients with advanced melanoma

Janice M. Mehnert, Ann W. Silk, Yu Wen, J. H. Lee, Liesel Dudek, Byeong-Seon Jeong, Jiadong Li, Jason M. Schenkel, Evita Sadimin, Michael Kane, Hongxia Lin, Weichung J. Shih, Andrew Zloza, Suzie Chen, James. S. Goydos

Accepted manuscript online: 17 February 2018
DOI: 10.1111/pcmr.12694

Int. J. Mol. Sci. 201819(2), 607; doi:10.3390/ijms19020607 (registering DOI)

Nanomechanical Phenotype of Melanoma Cells Depends Solely on the Amount of Endogenous Pigment in the Cells

Michal Sarna, Andrzej Zadlo, Barbara Czuba-Pelech  and Krystyna Urbanska
Received: 19 December 2017; Accepted: 7 February 2018; Published: 18 February 2018

Journal of Extracellular Vesicles
Volume 7, 2018 – Issue 1

Immunoaffinity-based isolation of melanoma cell-derived exosomes from plasma of patients with melanoma

Priyanka Sharma,Sonja Ludwig,Laurent Muller,Chang Sook Hong,John M Kirkwood,Soldano Ferrone & show all
Article: 1435138 | Received 12 Sep 2017, Accepted 26 Jan 2018, Published online: 15 Feb 2018

Science Signaling

Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis

Rakshamani Tripathi1Leann S. Fiore1Dana L. Richards2Yuchen Yang3Jinpeng Liu4Chi Wang4, and Rina Plattner1,*
Sci. Signal.  20 Feb 2018:
Vol. 11, Issue 518, eaao0422
DOI: 10.1126/scisignal.aao0422

Dove Press

Role of ubenimex as an anticancer drug and its synergistic effect with Akt inhibitor in human A375 and A2058 cells

Authors Wang X, Liu Y, Wu R, Guo F, Zhang L, Cui M, Wu X, Zhang Y, Liu W
Received 19 November 2017
Accepted for publication 12 January 2018
Published 22 February 2018 Volume 2018:11 Pages 943—953

Dove Press

Characterization of luteinizing hormone-releasing hormone receptor type I (LH-RH-I) as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines

Authors Sipos E, Dobos N, Rozsa D, Fodor K, Olah G, Szabo Z, Szekvolgyi L, Schally AV, Halmos G
Received 3 August 2017
Accepted for publication 25 November 2017
Published 22 February 2018 Volume 2018:11 Pages 933—941

Epidemiology of Melanoma.


Matthews NH2Li WQ2,3Qureshi AA2,3,4,5Weinstock MA2,3,6,5Cho E2,3,4.


In: Ward WH1Farma JM1, editors.


Cutaneous Melanoma: Etiology and Therapy [Internet]. Brisbane (AU): Codon Publications; 2017 Dec. Chapter 1.

The Lancet

Adjuvant vemurafenib in resected, BRAFV600 mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

Michele Maio, Karl Lewis, MD, Prof Lev Demidov, MD, Mario Mandalà, MD, Igor Bondarenko, MD, Paolo A Ascierto, MD, Christopher Herbert, MD, Prof Andrzej Mackiewicz, MD, Prof Piotr Rutkowski, MD, Alexander Guminski, PhD, Grant R Goodman, MD, Brian Simmons, PharmD, Chenglin Ye, PhD, Yibing Yan, PhD, Prof Dirk Schadendorf, MD and the  BRIM8 Investigators
Listed in the appendix
Published: 21 February 2018

Cancer Immunology Research

Quantitative Analysis of Immune Infiltrates in Primary Melanoma

Robyn D. Gartrell, Douglas K. Marks, Thomas D. Hart, Gen Li, Danielle R. Davari, Alan Wu, Zoe Blake, Yan Lu, Kayleigh N. Askin, Anthea Monod, Camden L. Esancy, Edward C Stack, Dan Tong Jia, Paul M. Armenta, Yichun Fu, Daisuke Izaki, Bret Taback, Raul Rabadan, Howard L. Kaufman, Charles G. Drake, Basil A. Horst and Yvonne M. Saenger
DOI: 10.1158/2326-6066.CIR-17-0360

International Journal of Cancer

Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis

Upekha E. Liyanage, Matthew H. Law, Jue Sheng Ong, Anne E. Cust, Graham J. Mann, Sarah V. Ward, Melanoma Meta-analysis Consortium, Puya Gharahkhani, Mark M. Iles, Stuart MacGregor

Accepted manuscript online: 22 February 2018
DOI: 10.1002/ijc.31334

JAMA Dermatology

Dermoscopy and Overdiagnosis of Melanoma In Situ

Kaitlin L. Nufer, BBiomedSci1Anthony P. Raphael, PhD1H. Peter Soyer, MD, FACD, FAHMS1
JAMA Dermatol. Published online February 21, 2018. doi:10.1001/jamadermatol.2017.6448

JAMA Dermatology

Accuracy of Dermoscopic Criteria for the Diagnosis of Melanoma In Situ

Aimilios Lallas, PhD1Caterina Longo, PhD2Marco Manfredini, MD3; et alElisa Benati, MD2Graziella Babino, MD4Chiara Chinazzo, MD4Zoe Apalla, PhD1Chryssoula Papageorgiou, MD1Elvira Moscarella, MD4Athanassios Kyrgidis, PhD2Giuseppe Argenziano, PhD4
JAMA Dermatol. Published online February 21, 2018. doi:10.1001/jamadermatol.2017.6447

International Journal of Cancer

Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis

Authors Upekha E. Liyanage1 Matthew H. Law , 1 , Jue Sheng Ong1 , Anne E. Cust2,7 , Graham J. Mann3,7, Sarah V. Ward4,6 , Melanoma Meta-analysis Consortium*, Puya Gharahkhani1 , Mark M. Iles5 , Stuart MacGregor1
‘Accepted Article’, doi:10.1002/ijc.31334

Cancer Prevention Research

Marshaling the Translational Potential of MC1R for Precision Risk Assessment of Melanoma

Peter A. Kanetsky and Jennifer L. Hay
DOI: 10.1158/1940-6207.CAPR-17-0255

International Journal of Oncology

Cutaneous melanoma: From pathogenesis to therapy (Review)

Giulia C. Leonardi, Luca Falzone, Rossella Salemi, Antonino Zanghì, Demetrios A. Spandidos, James A. Mccubrey, Saverio Candido, Massimo Libra
Published online on: February 27, 2018


Abscopal Effect in a Stage IV Melanoma Patient who Progressed on Pembrolizumab

James M. Tsui Catalin Mihalcioiu Fabio L. Cury 
Published: February 27, 2018
DOI: 10.7759/cureus.2238
Cite this article as: Tsui J M, Mihalcioiu C, Cury F L (February 27, 2018) Abscopal Effect in a Stage IV Melanoma Patient who Progressed on Pembrolizumab. Cureus 10(2): e2238. doi:10.7759/cureus.2238

International Journal of Cancer
Letter to the Editor

Immigration is the most likely reason for the generational change in melanoma incidence in Queensland, Australia

Dr. D Czarnecki MD MBBS

Accepted manuscript online: 28 February 2018
DOI: 10.1002/ijc.31348