Measurement of 45 cytokine, chemokine and growth factors in established cell culture supernatants and autologous serum from advanced melanoma patients
Source: MDLinx, January 2021
In the present study, the researchers sought to assess the pattern of soluble factors produced by premetastatic and metastatic melanoma established cultures and to ascertain if these factors can be detected in the autologous serum of malignant melanoma patients.
The findings demonstrated that both melanoma cultures had a common profile of 27 soluble factors mainly characterized by the high expression of VEGF-A, IL-6, MCP-1, IL-8, and SDF-1.
