Protein molecule link to melanoma outcomes

Source: The Sydney Morning Herald, June 2022

South Australian researchers are working to improve outcomes for skin cancer patients after discovering a particular protein may determine the fate of people with the disease.

A team from the University of South Australia’s Centre for Cancer Biology has identified the desmoglein-2 (DSG-2) protein and found melanoma patients who express it are two-and-a-half times more likely to die within 10 years.

Initial lab work has uncovered how to block the protein using nanotechnology, and research efforts will now look at ways to better isolate those patients most a risk.

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