First in the world melanoma trial to breakthrough barriers

Source: Alfred Health, February 2023

A first in the world trial looking at new treatment options for patients with melanoma that has spread to the brain is set to commence at The Alfred, potentially helping patients add years to their lives.

The BETTER trial will investigate whether a specific combination of immunotherapy drugs and targeted radiotherapy can improve outcomes for patients with melanoma brain metastases, who often have a poor prognosis and short life expectancy.

Dr Malaka Ameratunga, head of Molecular Oncology and Rare Cancers at The Alfred and co-chair of the trial, said the research could represent a significant breakthrough for patients previously considered too unwell to participate in trials.

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