Efficacy Shown for New Melanoma Therapeutic Vaccine
Source: Health Day, December 2023
FRIDAY, Dec. 15, 2023 (HealthDay News) — In a recent trial, a new melanoma vaccine, mRNA-4157 (V940), when taken in combination with Keytruda (pembrolizumab), was found to be effective in battling the deadly skin cancer.
People with advanced melanomas who received the vaccine plus Merck’s cancer drug Keytruda were 49 percent less likely to die or have their cancer return after three years than those who were given only Keytruda, vaccine maker Moderna Inc. announced Friday.
“Importantly for this technology, the… study was the first demonstration of efficacy for an investigational mRNA cancer treatment in a randomized clinical trial and the first combination therapy to show a significant benefit over Keytruda alone in adjuvant melanoma," Moderna Senior Vice President Kyle Holen, M.D., said in a company news release. “We look forward to sharing these data with people impacted by this disease and the broader scientific community."