Dr. Eroglu on the Utilization of ctDNA in Melanoma

Source: OncLive, March 2022

Zeynep Eroglu, MD, medical oncologist, Department of Cutaneous Oncology, Moffitt Cancer Center, assistant professor, Department of Oncologic Sciences, the University of South Florida, Morsani College of Medicine, discusses the utilization of circulating tumor DNA (ctDNA) in patients with melanoma.

Identifying a noninvasive biomarker, which are seen in other solid tumors, remains a challenge for patients with melanoma, Eroglu says. As a result, imaging or clinical exams are utilized to monitor patients for recurrence or progression while on treatment or following surgery, Eroglu explains. Time limits the frequency PET or CT scans that can be conducted on a given patient, making those methods less reliable for identifying disease recurrence or progression, Eroglu adds.