Dosing and Regimen Changes Promote Tolerability in Advanced Melanoma

Source: Targeted Oncology, March 2024

During a Targeted Oncology™ Case-Based Roundtable™ event, Michael B. Atkins, MD, discussed dosing considerations and toxicity when choosing combination treatment for patients with melanoma. This is the second of 2 articles based on this event.

DISCUSSION QUESTIONS

  • Are you familiar with the RELATIVITY-047 (NCT03470922) data on nivolumab plus relatlimab (Opdualag) vs nivolumab (Opdivo) alone?
  • What are your reactions to these data?

TARAL PATEL, MD: I am familiar with the data, but…50% of patients may [have] prolonged remissions…with ipilimumab [Yervoy] plus nivolumab, so how we can follow 2- to 3-year data and change the standard of care?1 That’s my biggest obstacle to changing the treatment options.

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