Does very early timing of lymph node surgery after resection of the primary tumour improve the clinical outcome of patients with melanoma?

Source: MDLinx, September 2020

Researchers investigated if the clinical outcome of patients with cutaneous melanoma could be impacted by very early timing of sentinel lymph node biopsy (SLNB) post-resection of the primary tumour, or by timing of complete lymph node dissection (CLND) following SLNB, vs longer time intervals. Experts analyzed a cohort comprising 896 patients with melanoma who had undergone SLNB.

They defined an interval between primary resection and SLNB or between SLNB and CLND of up to 7 days as very early (VE-SLNB and VE-CLND, respectively).

They compared this time span with intervals of > 7 days.