Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ12,14 prostamide J2

Source: docwirenews, January 2021

Metastatic melanoma is the most deadly skin neoplasm in the United States.

Outcomes for this lethal disease have improved dramatically due to the use of both targeted and immunostimulatory drugs.

Immunogenic cell death (ICD) has emerged as another approach for initiating antitumor immunity.

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