Contrast-enhanced ultrasound with perflubutane for sentinel lymph node mapping in cutaneous melanoma: A pilot study

Source: MDLinx, April 2019

In this single-arm pilot study in a swine animal model, authors estimated the accessibility of contrast-enhanced ultrasound (CEUS) to recognize the sentinel lymph node (SLN) associated with cutaneous melanoma. They observed 5 primary cutaneous melanomas with a mean area of 4.36?±?4.75?cm2 and Breslow depth of 3.6?±?1.5?mm. They also recognized 6 SLN with CEUS whereas 9 were identified with vital blue (VB) dye. They found histologically confirmed metastatic melanoma in 67% of SLNs identified by CEUS and 44% candidate SLNs identified by VB.

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