Cancer cells: How they shrink or grow larger to survive

Source: Medical News Today, February 2023

• Researchers at The Institute of Cancer Research (ICR), London are reporting that cancer cells have the ability to change their size to adapt to various challenges in their environment, including drug treatment.
• By using biochemical profiling and mathematical analysis, the researchers identified genetic changes that contribute to the size differences in cancer cells.
• The research suggests that smaller cancer cells could be targeted with chemotherapy and targeted drugs, while larger cancer cells may respond better to immunotherapy.A new study, published in the journal Science Advances and funded by The Institute of Cancer Research, is using advanced image analysis and DNA/protein examination to investigate the size regulation of melanoma cells, a type of skin cancer.

Melanoma can be caused by distinct genetic mutations. Two of the most common are a BRAF gene mutation, which is present in about 50% of cases, and an NRAS mutation,
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