Breslow Thickness’s Prognostic Significance in Acral Melanoma

Source: Physicians Weekly, February 2023

The following is a summary of “Prognostic impact of Breslow thickness in acral melanoma: A retrospective analysis,” published in the December 2022 issue of Dermatology by Wei, et al.

There wasn’t much data to support the predictive significance of tumor thickness in patients with acral melanoma (AM). For a study, researchers sought to ascertain how Breslow thickness in AM affected prognosis.

Patients diagnosed with localized AM between January 1, 2000, and December 31, 2017, were recruited in the multicenter trial. The Kaplan-Meier approach was used to determine the melanoma-specific survival (MSS) in various tumor thickness strata (T1-T4: ?1, >1-2, >2-4, >4 mm, respectively). The log-rank test and multivariable Cox regression were used for comparisons.

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