Incidence and Risk of Second Primary Melanoma Vary by Race/Ethnicity

Source: Cancer therapy Advisor, October 2024

New data suggest that, among patients with first primary cutaneous melanoma, White patients have the highest absolute risk of second primary melanoma. However, Black and Asian or Pacific Islander patients have the highest relative risk of second primary melanoma when compared to the general population. These data were published in JAMA Dermatology.

For this study, researchers analyzed 546,756 patients with first primary cutaneous melanoma diagnosed during 2000-2019. The vast majority of patients were White (96%), but the cohort also included patients who were Hispanic (3.1%), Asian or Pacific Islander (0.6%), Black (0.4%), and American Indian or Alaska Native (0.2%).

The researchers found that the absolute incidence of second primary melanoma was highest among White patients, followed by American Indian or Alaska Native, Hispanic, Black, and Asian or Pacific Islander patients.

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