Novel Bispecific Antibody Fusion Protein Earns FDA Fast Track in Melanoma

Source: Targeted Oncology, September 2024

IBI363 has earned fast track designation from the FDA for the treatment of previously treated unresectable advanced melanoma.

  • The FDA has granted a fast track designation to IBI363 for the treatment of unresectable locally advanced or metastatic melanoma that has progressed following at least 1 line of systemic therapy, including a PD-(L)1 inhibitor.
  • IBI363 is an investigational PD-1/IL-2? bispecific antibody fusion protein.
  • Phase 1/2 trials are evaluating the agent’s safety in advanced malignant tumors.

IBI363, a PD-1/IL-2? bispecific antibody fusion protein, has been granted fast track designation from the FDA in patients with unresectable locally advanced or metastatic melanoma who have progressed following at least 1 line of systemic therapy, including a PD-(L)1 inhibitor.

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