Microsatellites may be associated with poorer survival outcomes in melanoma
Source: Onc Live, November 2022
Varying therapies for the neoadjuvant and adjuvant treatment of melanoma based on staging continue to be explored with pembrolizumab (Keytruda) a common agent in both settings, according to Sapna Patel, MD.
Patel’s presentation at the 40th Annual CFS® meeting, “Neoadjuvant and Adjuvant Therapeutic Approaches for Melanoma” highlighted clinical trials such as phase 2 S1801 (NCT03698019) and discussed the role of pembrolizumab as well as agents nivolumab (Opdivo) plus ipilimumab (Yervoy) in the treatment paradigm.
In an interview with OncLive®, Patel, chair of the SWOG melanoma committee and an associate professor at The University of Texas MD Anderson Cancer Center in Houston, reviewed several key studies across stages of melanoma and emerging targeted therapies for patients with BRAF mutations.