Predictors of nonsentinel lymph node metastasis in cutaneous melanoma: A systematic review and meta-analysis

Source: MDLinx, December 2020

Researchers aimed to determine risk factors that can predict the risk of nonsentinel node metastases (NSNM) in this systematic review and meta-analysis.

Searching Medline, Web of Science, Embase, and Cochrane, 50 publications discussing predictive factors for NSNM were identified as suitable for additional analysis.

The following clinical and primary tumor factors were consistently recognized as risk factors for NSNMs: age > 50, T stage 3 or 4, Clark level IV/V, ulceration, microsatellitosis, lymphovascular invasion, nodular histology, and extremity vs trunk primary tumor location.

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