Predictors of Long-term Anxiety and Depression in Uveal Melanoma Survivors: A Cross-lagged Five-year Analysis

Source: docwirenews, August 2020

Cancer survivors commonly experience long-term anxiety and depression.

Anxiety and depression might result from problems emerging during survivorship rather than illness and treatment.

This study tested three potential causal paths: 1) concerns about physical symptoms and functional problems and fear of cancer recurrence (FCR) arising during survivorship directly cause anxiety and depression, 2) an indirect path whereby FCR mediates effects of concerns about physical symptoms and functional problems on anxiety and depression, and 3) a reciprocal path whereby anxiety and depression cause concerns about physical symptoms and functional problems and FCR, which exacerbate later anxiety and depression.

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