Factors Affecting Sentinel Node Metastasis in Thin (T1) Cutaneous Melanomas: Development and External Validation of a Predictive Nomogram
Source: MDLinx, May 2020
In view of the observation that for thin melanomas (T1; ? 1 mm), regional node metastasis determined by sentinel node biopsy (SNB) is an important prognostic factor, researchers here investigated the determinants of sentinel node (SN) status for incorporation into an externally validated nomogram to better define patients with T1 disease for SNB. From 2001 to 2018, 3,666 patients with T1 disease consecutively underwent treatment at the Istituto Nazionale Tumori (Milan, Italy), these patients were included in the development cohort. The validation cohort comprised 4,227 patients with T1 disease treated at 13 other European centers over the same period.
