Dr. Postow on Entrectinib in Melanoma

Source: OncLive, November 2017

Michael A. Postow, MD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses the role of entrectinib for patients with NTRK fusion-positive melanoma.
Following more comprehensive molecular profiling, there are different genetic fusion events or other types of activating mutations, states Postow. There is a new fusion that has been discovered around NTRK that affects patients with advanced melanoma.
There are some promising strategies being used to target NTRK fusion, such as entrectinib, Postow explains.