NeoVax Demonstrates Long-Lasting Durable Responses in Melanoma

Source: OncLive, February 2021

Neoantigen long peptide vaccines (NeoVax) continued to show durable T-cell responses in patients with high-risk melanoma that persisted 4 years after initial vaccination, highlighting the ability of personalized cancer vaccines to provide long-term control against some cancers, according to results of a phase 1 study (NCT01970358) published in Nature Medicine.1,2

In the small study of 8 patients who had previously received surgery for advanced melanoma, and were considered to be at high-risk of recurrence, NeoVax was administered at a median 18 weeks after resection.

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