Combos Lead Excitement in BRAF+ Melanoma, but More Pain Points are Ready to be Tackled

Source: Dermatology Times, March 2021

Therapeutic approaches to target the metabolic pathways, an enhanced understanding of how to utilize triplet regimens, and improving outcomes for patients with brain metastases are all areas being tackled in the setting of advanced BRAF-positive melanoma, explained Michael A. Davies, MD, PhD.

The invigorating research efforts build up on the 3 BRAF/MEK inhibitor combinations currently being used in this patient population: dabrafenib (Tafinlar) plus trametinib (Mekinist), vemurafenib (Zelboraf) and cobimetinib (Cotellic), and encorafenib (Braftovi) plus binimetinib (Mektovi).

READ THE ORIGINAL FULL ARTICLE