Study Identifies Genes That Help Drive Growth in Melanoma Subtypes

Source: Dana-Farber Cancer Institute, November 2020

Favoritism or impartiality? Do the four genomic subtypes of melanoma have a bias toward certain mutated genes and gene pathways, or do they welcome all mutations equally?

Answering that question has been especially difficult because of cutaneous melanoma’s high mutation rate — the profusion of misspelled, severed, out-of-place, missing-in-action, or overabundant genes found in melanoma skin tumors.

This roar of genetic error makes it particularly difficult to discern the whisper of gene mutations that actually drive the disease.

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