Second primary melanomas show no increased mortality risk

Source: Heolio, May 2022

Patients with second primary melanomas showed significant survival advantage and thinner lesions compared with those with single primary melanomas, according to a study published in the Journal of the American Academy of Dermatology.

Melissa M. Sarver, MD, of Duke University School of Medicine, and colleagues noted that 1.3% to 8% of patients who develop a single primary melanoma have an increased risk for developing multiple primary melanomas (MPMs), which includes a subset of whom will develop a “second primary melanoma” within 3 months of the first lesion.

To examine tumor and patient characteristics related to this aspect, the researchers conducted a retrospective study that comprised three factors: patients with a single primary melanoma, patients with a second primary melanoma occurring within 3 months from initial diagnosis (synchronous group) and patients with a second primary melanoma diagnosed after 3 months from initial diagnosis (asynchronous group).