Really Low-Risk?

Source: Cancer Network, June 2019

Even thin T1 nodular primary melanomas are associated with “a constellation of aggressive characteristics” that might worsen patient prognosis compared with superficial spreading melanoma, according to findings from an international study published in the Journal of the National Cancer Institute.

The findings challenge longstanding assumptions about the life-threatening aggressiveness of nodular melanomas.

Nodular melanoma accounts for a disproportionate number of melanoma deaths. That has long been widely assumed to be due to greater Breslow thickness at the time of diagnosis, Alexander J. Stratigos, MD, of the National and Kapodistrian University of Athens, Andreas Sygros Hospital, in Athens, told Cancer Network.

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