Prior Treatment Confers Reduced Responses With Adoptive Transfer of TIL Therapy in Metastatic Melanoma

Source: OncLive, August 2021

Prior treatment with PD-1 or MAPK inhibitors resulted in lower objective response rates (ORRs) with adoptive cell transfer (ACT) of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma vs patients who were naïve to these agents, according to findings from a retrospective analysis that were published in Clinical Cancer Research.1

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