New nanosystem enhances treatment for melanoma in animal models

Source: ScienceDaily, September 2020

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU’s Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

The nanocarrier is a biocompatible and biodegradable polymer, which comprises repeating units of glutamic acids.

It packages together two drugs belonging to different families with proven efficacy for the treatment of melanoma: BRAF inhibitors (Dabrafenib) and MEK inhibitors (Selumetinib, approved for use in children with neurofibromatosis type I).

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