Researchers sought to determine the potential mechanisms underlying melanoma metastasis.
Archive | Scientific Publications
Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
Posted in Melanoma News, Publications, Scientific Publications
Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma
The use of MEK inhibitors in the therapy of uveal melanoma (UM) has been investigated widely but has failed to show benefits in clinical trials due to fast acquisition of resistance.
Posted in Melanoma News, Publications, Scientific Publications
AP-2alpha-mediated activation of E2F and EZH2 drives melanoma metastasis
To clarify the role of the AP-2alpha transcription factor, which is encoded by TFAP2A, in melanoma metastasis, researchers undertook this study.
Posted in Melanoma News, Publications, Scientific Publications
STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
BACKGROUND: Resistance to an immune checkpoint inhibitor (ICI) is a major obstacle in cancer immunotherapy.
Posted in Melanoma News, Publications, Scientific Publications
