Age-related changes in skin structure & lymphatic system promote melanoma metastasis
Source: ECancer News, October 2018
Changes in the structure of the skin and the lymphatic system that occur with the natural aging process create permissive conditions for melanoma metastasis, according to two studies by The Wistar Institute.
These changes are caused by loss of the HAPLN1 protein, which is part of the extracellular matrix, during aging.
