31-Gene Expression Profile Test Improves Risk Assessment in Cutaneous Melanoma

Source: OncLive, April 2021

Combining the 31-gene expression profile (GEP) test with current American Joint Committee on Cancer (AJCC) staging guidelines may improve risk assessment in patients with cutaneous melanoma, as well as determine which patients could be candidates for more intense follow-up, according to data from a multicenter, prospective cohort study published in JCO Precision Oncology.1

The 31-GEP test proved to be significant for 3-year recurrence-free survival (RFS), distant metastasis-free survival (DMFS), and overall survival (OS) in a univariate analysis, as well as a significant independent predictor of RFS, DMFS, and OS in a multivariable analysis.

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